Arjunolic acid is one such novel phytomedicine with multifunctional therapeutic applications. It is a triterpenoid saponin, isolated earlier from. This review highlights the beneficial role of arjunolic acid, a naturally occurring chiral triterpenoid saponin, in various organ pathophysiology and the underlying . Abstract. Arjunolic acid, the major extractable constituent of the heavy wood of Ter- minalia Arjuna, has the potential to be used as a rigid and functional.
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It also plays an effective role in exerting protection against both type I and type II diabetes and also ameliorates diabetic renal dysfunctions. Quantitative metabolomics services for biomarker discovery and validation. A molecular entity capable of donating a hydron to an acceptor Br o nsted base.
Articles by Sarkar, S. Your source for quantitative metabolomics technologies and bioinformatics. Value Source arjunoolic acid. Child entities Include all the children relationships for this entity. Phytochemicals have gained attention as alternative therapeutics for managing cardiovascular diseases.
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Within the cell, arjunolic acid is primarily located in the membrane predicted from logP and cytoplasm. Arjunolic acid exists as a solid and is considered to be practically insoluble in water and relatively neutral. Esters of ajunolic acid arjuonlic as gelators of a wide variety of organic liquids.
Apart from its pathophysiological functions, it possesses dynamic insecticidal property and it is used as a structural molecular framework in supramolecular chemistry and nanoscience.
Arjunolic acid: a novel phytomedicine with multifunctional therapeutic applications.
Journal of Lipid Research. You are using an unsupported browser.
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An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. Cardiac hypertrophy and associated heart fibrosis remain a major cause of death worldwide.
Nat Rev Mol Cell Biol.
Arjunolic acid | C30H48O5 – PubChem
Any intermediate or product resulting from metabolism. It is a triterpenoid saponin, isolated earlier from Terminalia arjuna and later from Combretum nelsonii, Leandra chaeton etc. AR3 conducted protein modeling and protein-protein docking and analysed the data with SS3.
These include the extract from the plant Terminalia arjuna which is a popular cardioprotectant and may prevent or slow progression of pathological hypertrophy to heart failure. A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. Personalised view Create your own personalised ontology view, if you wish to remove any entity from your future visualisations please right click the entity e.
JS2 and BK2 did most of the bioinformatic and biophysical studies and analysed the data. Herbal plants with antioxidant activities are widely used in Ayurvedic medicine for cardiac and other problems. Triterpenoid hydroxysteroid Hydroxysteroid Steroid Cyclic alcohol Secondary alcohol Carboxylic acid derivative Carboxylic acid Monocarboxylic acid or derivatives Hydrocarbon derivative Organic oxide Organic oxygen compound Alcohol Carbonyl group Organooxygen compound Primary alcohol Aliphatic homopolycyclic compound.
Arjunolic acid, also known as arjunolate, belongs to the class of organic compounds known as triterpenoids.
Additives, flavors, and ingredients. VT4 did extraction and purification of arjunolic acid used in the study. Property Value Source Water Solubility. The term ‘metabolite’ subsumes the classes commonly known as primary and secondary metabolites.
The scientific basis for the use of arjunolic acid as cardiotonic in Ayurvedic medicine is proven by its vibrant functions such as prevention of myocardial necrosis, platelet aggregation and coagulation and lowering of blood pressure, heart rate and cholesterol levels. Bronsted acid A molecular entity capable of donating a hydron to an acceptor Br o nsted base.
Its antioxidant property combined with metal chelating property protects organs from metal and drug induced toxicity. This makes arjunolic acid a potential biomarker for the consumption of these food products.
Epub Aug Adipose tissue function and plasticity orchestrate nutritional adaptation. Services Email this article to a friend Alert me when this article is cited Alert me if a correction is posted Alert me when eletters are published Similar articles in this journal Similar articles in PubMed Download to citation manager Request Permissions.
These are terpene molecules containing six isoprene units. Full view Show me all the nodes in this graph. Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search.
The mechanism of cytoprotection conferred by arjunolic acid can be explained by its property to reduce the oxidative stress by enhancing the antioxidant levels. Our data revealed that AA significantly represses collagen expression and improves cardiac function during hypertrophy. You’ll be in good company.