Sobre el 70% de los casos se produce después de un procedimiento dental Palabras clave: osteonecrosis, bifosfonatos, osteonecrosis de los maxilares. os riscos das condições orais e sistêmicas que envolvem o uso de bifosfonatos. para tratar a estos pacientes en las distintas especialidades odontologicas. La prevalencia de avulsión dental supone del 0, % de todas las lesiones .. (58), acetazolamida (59), bifosfonatos (60,61)o derivado de la matriz del.

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Sociedad de Periodoncia de Chile. Los resultados indican, bifosfonahos los pacientes en mayor riesgo de desarrollar osteonecrosis de los maxilares son aquellos que reciben terapia con bifosfonatos nitrogenados intravenosos.

El manejo de las lesiones es de alta complejidad. In recent years, due to different causes, an increasing number of patients are under medical treatment with bisphosphonates. These drugs might be associated with the growing of spontaneous ulceration of the oral mucosa and osteonecrosis of the jaws. The purpose of this review is to describe the characteristics of bisphosphonates, its mechanism of action, clinical manifestation of osteonecrosis of the jaws, therapeutic management and prevention.

Patients treated with intravenous nitrogen-containing bisphosphonates, have a major risk to develop osteonecrosis.

The mandible is more commonly affected than the maxilla. Probably the origin of the osteonecrosis of the jaws is a decreased microcirculation and a limited bone turnover due to bisphosphonates, leading to diminish their healing capacity and regeneration of the tissues. The management of the lesions is difficult. Palliative treatment is proposed with oral rinses and systemic antibiotic therapy.

Protocolo de atendimento para pacientes com osteonecrose by on Prezi

Removal of necrotic bone is recommended in severe cases. In conclusion, is necessary to know this condition for an early diagnosis and treatment, so to prevent its apparition.


In this way, it is recommendable to do an oral examination and diagnosis, to treat active oral infections and eliminate sites at high risk for infection before getting the bisphosphonate therapy started. Furthermore, to avoid surgical procedures in odontolovia patients. Scielo, ScienceDirect, Latindex, Redalyc. Osteonecrosis de los Maxilares Asociado a Terapia con Bifosfonatos: Abstract In recent years, due to different causes, an increasing number of patients are under medical treatment with bisphosphonates.

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Tratamiento de la litiasis renal con bifosfonatos

Quim Nova, 28pp. Heterocycle-containing bisphosphonates cause apoptosis and inhibit bone reorption by preventing protein prenylation: J Bone Miner Res, 13pp. Bisphosphonates and osteonecrosis of the jaws: Implants and oral bisphosphonates: J Periodontol, 78pp.

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Nature and frequency of bisphosphonateassociated osteonecrosis of the jaws in Australia.

Osteonecrosis de los Maxilares Asociado a Terapia con Bifosfonatos: Situación Actual

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